Antibiotics and Competition

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Effects of Competition between Healthcare Providers on Prescription of Antibiotics

The introduction of antibiotics as a medical treatment after World War II helped to dramatically increase life expectancy in the industrialized world. However, over-prescription of antibiotics during the last few decades has led to a sharp increase in multi-resistant bacteria, disarming once powerful anti-pathogens. This paper investigates the effects of increased competition between healthcare...

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A competition-based assay for the screening of species-specific antibiotics.

OBJECTIVES To develop a high throughput screening-compatible assay for the selection of species-specific antibiotics that do not harm human cells. METHODS Staphylococcus aureus and human reporter cells continuously generating a fluorescence signal were competitively co-cultivated. The fluorescence signals were determined in the presence and absence of the specific antibiotic streptomycin and ...

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ژورنال

عنوان ژورنال: Nature

سال: 1944

ISSN: 0028-0836,1476-4687

DOI: 10.1038/153170a0